SmartTots (Strategies for Mitigating Anesthesia-Related neuroToxicity in Tots) Public-Private Partnership

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Opportunity ID: 329611
Opportunity Number: FOR-FD-20-25
Opportunity Title: SmartTots (Strategies for Mitigating Anesthesia-Related neuroToxicity in Tots) Public-Private Partnership
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Agriculture
Consumer Protection
Science and Technology and other Research and Development
Category Explanation:
CFDA Number(s): 93.103
Eligible Applicants: State governments
County governments
City or township governments
Special district governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Additional Information on Eligibility:
Agency Code: HHS-FDA
Agency Name: Department of Health and Human Services
Food and Drug Administration
Posted Date: Oct 28, 2020
Last Updated Date: Oct 28, 2020
Estimated Synopsis Post Date:
Fiscal Year: 2021
Award Ceiling:
Award Floor:
Estimated Total Program Funding:
Expected Number of Awards:
Description: Millions of children receive anesthetic and sedation drugs each year for surgical and non-surgical procedures. Over the past two decades, an expanding body of data from animal studies have demonstrated that exposure of the developing brain to anesthetic and sedation agents is associated with neurodegeneration and long-term, likely permanent, deficits in cognitive function and behavior. Under the Critical Path Initiative, SmartTots Public-Private Partnership (PPP) was established to address the critical public health issues associated with the safe use of anesthetic agents and sedatives in young children. The objective of this cooperative agreement is to continue bridging the knowledge gaps, elucidating the risks related to the use of anesthetic and sedative agents in children, and developing strategies for optimizing brain health in children who require anesthesia and sedation care.
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