Notice of Intent to Publish Funding Opportunity Announcements for a Lung Transplant Consortium (LTC) (U01)

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Opportunity ID: 325183
Opportunity Number: NOT-HL-20-752
Opportunity Title: Notice of Intent to Publish Funding Opportunity Announcements for a Lung Transplant Consortium (LTC) (U01)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
CFDA Number(s): 93.838
Eligible Applicants: State governments
County governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility:
Agency Code: HHS-NIH11
Agency Name: Department of Health and Human Services
National Institutes of Health
Posted Date: Mar 05, 2020
Last Updated Date: Mar 05, 2020
Estimated Synopsis Post Date: Dec 01, 2020
Fiscal Year: 2021
Award Ceiling: $1,750,000
Award Floor:
Estimated Total Program Funding:
Expected Number of Awards:
Description: The National Heart, Lung and Blood Institute (NHLBI) intends to publish two companion Funding Opportunity Announcements (FOAs), one to solicit applications for lung transplant clinical centers (CCs) and another for a data coordinating center (DCC), to form a cooperative multi-site Lung Transplant Consortium (LTC). The LTC will seek to harmonize and standardize data and biospecimen collection among lung transplant donors, waitlist candidates, and recipients across participating lung transplant centers. Additionally, the LTC will support observational studies evaluating lung transplant selection criteria and clinical management strategies as they relate to donor lung utilization and/or post-transplant outcomes including primary graft dysfunction (PGD) and acute lung allograft dysfunction (ALAD). Beyond improving our understanding of factors that influence the incidence, severity, and management of PGD and ALAD following transplantation, harmonization of research data and biospecimen collection across lung transplant centers will serve as a critical first step in facilitating future clinical trials that aim to improve donor lung utilization and short- and long-term outcomes for transplant recipients. This Notice is being provided to encourage investigators with expertise and insights in the area of lung transplantation to begin to consider applying for these new FOAs and allow sufficient time for these potential applicants to develop meaningful collaborations and responsive projects. The FOAs are expected to be published in December 2020 with an anticipated application receipt date in March 2021. NHLBI intends to utilize the U01 activity code, a cooperative agreement, for these FOAs. Anticipated details of the planned FOAs are provided below.
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