Notice of Intent to Publish a Funding Opportunity Announcement for Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite (UG3/UH3) with Coordinating Center (U24)

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Opportunity ID:329680
Opportunity Number:NOT-HL-20-820
Opportunity Title:Notice of Intent to Publish a Funding Opportunity Announcement for Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite (UG3/UH3) with Coordinating Center (U24)
Opportunity Category:Discretionary
Opportunity Category Explanation:
Funding Instrument Type:Cooperative Agreement
Category of Funding Activity:Health
Category Explanation:
CFDA Number(s):93.233
93.837
93.839
93.840
Eligible Applicants:State governments
County governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility:
Agency Code:HHS-NIH11
Agency Name:Department of Health and Human Services
National Institutes of Health
Posted Date:Nov 03, 2020
Last Updated Date:Nov 03, 2020
Estimated Synopsis Post Date:Feb 01, 2021
Fiscal Year:2022
Award Ceiling:$1,001,000
Award Floor:
Estimated Total Program Funding:
Expected Number of Awards:7
Description:The Division of Cardiovascular Sciences within the National Heart, Lung, and Blood Institute (NHLBI) intends to publish a milestone-driven Funding Opportunity Announcement (FOA) to invite applications for research on Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite (UG3/UH3 Clinical Trial Required) and a companion FOA for a Coordinating Center (U24 Clinical Trial Not Required). The FOAs are expected to be published in winter 2021 with an expected application due date in spring 2021. This Notice of Intent to Publish is to enable potential applicants sufficient time to develop competitive applications that propose to test the effectiveness of an implementation-ready intervention designed to determine if a cardiovascular health (CVH) promotion module delivered within the context of a home visiting program can enhance maternal and early childhood CVH and address CVH disparities in mothers and children (0-5 years). The study population includes those who are of low socioeconomic status, or live in low resource or underserved rural or urban communities, or in diverse geographic regions of the U.S. with a high burden of cardiovascular disease risk factors. A FOA for clinical trials (UG3/UH3) will run in parallel with a companion FOA for an ENRICH Research Coordinating Center (U24). Key characteristics of the bi-phasic UG3/UH3 cooperative agreement mechanism (Clinical Trial Required) are that the FOA will support a milestone-driven planning phase (UG3), including feasibility studies and pilot trials for up to 2 years, with possible transition to an implementation phase (UH3) for up to five additional years. The total period of support may be up to 7 years. Only UG3 trials that meet NHLBI-approved scientific milestones and award requirements of the UG3 phase may transition to the UH3 phase. Applications must address planned activities for both the UG3 and UH3 phases. Details of the planned FOAs are provided below.
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