Notice of Intent to Publish a Funding Opportunity Announcement for Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium – Scientific Data Coordinating Center (SDCC) (U24 – Clinical Trial Not Allowed)

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Opportunity ID: 327570
Opportunity Number: NOT-DK-20-030
Opportunity Title: Notice of Intent to Publish a Funding Opportunity Announcement for Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium – Scientific Data Coordinating Center (SDCC) (U24 – Clinical Trial Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
CFDA Number(s):
Eligible Applicants: Public and State controlled institutions of higher education
Private institutions of higher education
Additional Information on Eligibility:
Agency Code: HHS-NIH11
Agency Name: Department of Health and Human Services
National Institutes of Health
Posted Date: Jun 08, 2020
Last Updated Date: Jun 08, 2020
Estimated Synopsis Post Date: Jul 15, 2020
Fiscal Year: 2021
Award Ceiling: $600,000
Award Floor:
Estimated Total Program Funding: $4,000,000
Expected Number of Awards: 1
Description: The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Environmental Health Sciences (NIEHS) intend to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to invite applications for research on Chronic Kidney Disease of Uncertain Etiology (CKDu) in Agricultural Communities. Included in this initiative will be a Scientific Data Coordinating Center (SDCC) to support and provide scientific guidance as part of the new consortium to study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE). The SDCC will guide the consortium as it develops protocols for epidemiologic studies. It will provide data management and analysis, as well as overall project management for the consortium. This collaborative research consortium will bring together a broad range of expertise and enable discovery science to understand the cause or causes of CKDu. The consortium will also work to identify potential therapeutic targets and public health interventions. The consortium will consist of a Scientific Data Coordinating Center, Field Sites, a Renal Analytic Core and the NIEHS Human Health Exposure Analysis Resource (HHEAR). The consortium will work together to develop common protocols for evaluation of participants who are currently affected with early manifestations of CKDu and controls, to define common strategies for biological sampling and environmental assessment, and to determine analytic strategies to best use the samples collected by the consortium. This FOA will not support intervention trials to prevent or treat CKDu. This FOA is intended to support only human studies and applications that include animal or model systems are not responsive . This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The FOA is expected to be published in Summer 2020 with an expected application due date in Fall 2020. This FOA will utilize the U24 activity code. Details of the planned FOA are provided below.
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