Implementation of population-based screening for new newborn conditions: Research studies to evaluate the feasibility and clinical validity in support of evidence based decision making.

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Opportunity ID:309315
Opportunity Number:RFA-EH-19-001
Opportunity Title:Implementation of population-based screening for new newborn conditions: Research studies to evaluate the feasibility and clinical validity in support of evidence based decision making.
Opportunity Category:Discretionary
Opportunity Category Explanation:
Funding Instrument Type:Cooperative Agreement
Category of Funding Activity:Health
Category Explanation:
CFDA Number(s):93.061
Eligible Applicants:State governments
Additional Information on Eligibility:This Notice of Funding Opportunity seeks to address and collect data on the unique challenges experienced by state newborn screening programs associated with the implementation of new conditions in a high throughput screening public health setting. Primary applicant eligibility for this funding opportunity announcement is limited to U.S. state (including the District of Columbia) or territorial governments or consortia comprised thereof.
Agency Code:HHS-CDC-HHSCDCERA
Agency Name:Department of Health and Human Services
Centers for Disease Control and Prevention – ERA
Posted Date:Sep 27, 2018
Last Updated Date:Sep 27, 2018
Estimated Synopsis Post Date:Nov 23, 2018
Fiscal Year:2019
Award Ceiling:$3,500,000
Award Floor:$0
Estimated Total Program Funding:$31,500,000
Expected Number of Awards:3
Description:The Centers for Disease Control and Prevention (CDC) National Center for Environmental Health (NCEH) Newborn screening programs test infants for diseases that require immediate medical treatment but are not apparent at birth. More than 4 million newborns are tested annually in the United States, and thousands of infants and children are saved from disability and death through early detection and treatment. Newborn screening practices, including the types of disorders for which newborns are screened, vary from state to state. The implementation of new conditions to the “Recommended Uniform Screening Panel” (RUSP) requires review of existing evidence that can be addressed by feasibility studies and a state-based pilot to assess the clinical validity of the screening test. Studies performed in the context of a high throughput newborn screening public health program will provide the data and insight necessary for effective evidence-based decision making when new conditions are being considered for addition to the RUSP. The purpose of this Notice of Funding Opportunity is to seek rigorous research that will improve evidence-based decision-making for national implementation of the addition of new conditions to the RUSP.
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