Assessing Immune Memory (AIM)

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Funding Opportunity ID:335379
Opportunity Number:HR001121S0037
Opportunity Title:Assessing Immune Memory (AIM)
Opportunity Category:Discretionary
Opportunity Category Explanation:
Funding Instrument Type:Cooperative Agreement
Other
Procurement Contract
Category of Funding Activity:Science and Technology and other Research and Development
Category Explanation:
CFDA Number(s):12.910
Eligible Applicants:Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility:All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.
Agency Code:DOD-DARPA-BTO
Agency Name:Department of Defense
DARPA – Biological Technologies Office
Posted Date:Aug 20, 2021
Close Date:Oct 26, 2021 See Full Announcement for details.
Last Updated Date:Aug 20, 2021
Award Ceiling:$0
Award Floor:$0
Estimated Total Program Funding:
Expected Number of Awards:
Description:Military service members rely on effective vaccination for the prevention of communicable disease as well as to guard against biothreat exposure. Many current vaccines lack durability (i.e., do not provide effective protection over long periods of time), and there are multiple pathogens and threats that lack prophylactic options altogether. It is currently impossible to predict vaccine durability from early response profiles, largely owing to ignorance of mechanisms underlying immune memory as well as an inability to measure the cellular contributors that invoke long-lasting immune protection. Formation of immune memory is a complex physiological process characterized by a diverse array of cellular interactions and signaling processes. AIM seeks to develop a platform capability to predict immune memory informed by a systems-level view of the host response to vaccination and its mechanisms.
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